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Systematic Reviews

A Step-by-Step PRISMA Systematic Review Workflow

Turn a messy literature search into a transparent, reproducible systematic review with PRISMA — from protocol to flow diagram, step by step.

The phdguide Research Team 25 June 2026 1 min read

A systematic review differs from a narrative one in a single word: reproducibility. Anyone should be able to follow your process and reach the same set of included studies. PRISMA is the standard that makes that possible.

1. Write a protocol first

Before searching, define your research question (often with a framework like PICO), your databases, your search strings, and your inclusion and exclusion criteria. Registering or at least documenting this protocol upfront prevents cherry-picking.

2. Search systematically

  • Choose databases deliberately (Scopus, Web of Science, and field-specific ones).
  • Build a Boolean search string from your key concepts and synonyms.
  • Record the exact strings and the number of hits per database — you'll report these.

3. Screen in stages

  1. 1Remove duplicates.
  2. 2Screen titles and abstracts against your criteria.
  3. 3Assess full texts for eligibility, recording a reason for every exclusion.
  4. 4Arrive at your final set of included studies.

4. Draw the PRISMA flow diagram

The flow diagram visualises the four stages — Identification, Screening, Eligibility, Included — with counts at each step. It is what lets a reader (and a reviewer) audit exactly how you went from thousands of records to your final sample.

Tip

Keep a synthesis matrix as you go — one row per included study, columns for method, sample, findings and quality. Every claim in your review should trace back to a row.

5. Synthesise and report

Synthesise thematically or, where the evidence supports it, with a meta-analysis. Report against the PRISMA 2020 checklist. For end-to-end help, see our literature review mentoring.

Frequently asked

Is PRISMA mandatory for a systematic review?+

It isn't universally mandatory, but many journals require PRISMA-compliant reporting, and reviewers increasingly expect the checklist and flow diagram.

How many studies should a systematic review include?+

There is no fixed number — it depends entirely on your question and criteria. What matters is that the search and screening were exhaustive and transparent.

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The phdguide Research Team
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We provide academic support, mentoring, analysis, editing and structuring — not authorship. Your work stays compliant with university policies.